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Title: Natural Products Isolation


Image of front cover of Natural Products Isolation

Edited by Richard J.P. Cannell

Humana Press Inc. (1998)

Format: hard cover, 15 chapters, 473 pages

Back cover

Natural Products Isolation
Edited by Richard J.P. Cannell - Glaxo Wellcome Research and Development, Stevenage, Herts, UK

     Natural Products Isolation provides a comprehensive introduction to techniques for the extraction and purification of natural products from all biological sources.  The book opens with an introduction to separations and chromatography and discusses the approaches to an isolation.   Experienced experimentalists describe a wide array of methods for isolation of both known and unknown natural products, including initial extraction, open-column chromatography, HPLC, countercurrent and planar chromatography, SFE, and crystallization.   Later chapters address specific issues in working with plants, marine organisms, water-soluble compounds, as well as scale-up, dereplication, and follow-up of a natural product lead.  For the less experienced, these chapters provide background information and hands-on advice--using real examples--about how to approach an extraction in general, when and how to apply a particular technique, and how to modify conditions according to the nature of the compound being isolated.

     Geared to scientists with little experience of natural products extraction, but offering even skilled researchers valuable advice and insight, Natural Product Isolation lays the foundation for the potential extractor to isolate natural substances efficiently.  Its methods and guidance will almost certainly play a major role in today's natural product discovery and development.

Features

  • Provides detailed hands-on methods for extracting and purifying natural products
  • Covers all practical aspects of natural product isolation
  • Includes baackground notes, practical guidance, and examples of all major techniques
  • Suitable for beginners with little previous experience
  • Covers all classes of natural product, with emphasis on unknown compounds

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